Atopic Dermatitis Topical Solution

Celfex AB is a co-development SPV with leading partners combining their capability to address unmet needs. We aspire to help children and adults suffering from Eczema (Atopic Dermatitis) — a first-of-its-kind stable formulation of Fexofenadine to be administered topically. Ready for Phase 2 study.

Strategic Partnership & Investment Inquiries

Our Ambition

A clinically approved solution to market by 2028 — a co-developed, orchestrated and holistic approach that considers all stakeholders, including care givers (parents) and patients, both adults and children.

Leading Intellectual Property

The drug designer is partnered in the journey and aligned to success-based clinical outcomes.

Clinical Development Plan

Practical and cost-effective. Holistic thinking, leveraging partnerships with aligned incentives.

Focus on Time to Value

Value to patients and value to investors. Clinical pathways driving fast value inflection and optionality for both OTC and prescription.

Future Roadmap

Reasonable claims to begin with — recognizing the multi-indication potential of this platform.

The Untapped Potential of Fexofenadine

An unmet need exists for cost-effective and tolerable treatment of Atopic Dermatitis. Our patent-granted topical formulation of Fexofenadine targets multiple pathways involved in the disease, offering a novel multi-action approach to treating eczema. Compared with oral administration today, Celfex applies the active ingredient where it is needed, thereby reducing possible liver toxicity.

Learn more about our science →
H1R blocking
Anti-inflammatory control
Dysbiosis control
Moisture retention
Barrier repair
Upregulation of antimicrobial peptides

A Large, Under-Served Market

Atopic dermatitis (eczema) affects millions worldwide, with the greatest unmet need among children. Celfex targets the mild-to-moderate segment with a cost-effective, once-daily solution.

$22.6B

Projected atopic dermatitis market by 2031

~20%

Of children affected by atopic dermatitis worldwide

75%

Of eczema patients are children — and, indirectly, their guardians (parents), our priority population

Once/day

Compliance-friendly topical lotion, OTC & prescription

Market figures based on independent valuation (DelveInsight). Celfex addresses an estimated 8.5% of the mild-to-moderate segment.

Our Clinical Plan

Celfex is built on a known molecule with an established safety profile. With Phase 1 complete, we are advancing into a Phase 2 bridge study.

COMPLETED

Preclinical & Phase 1

Proprietary once-daily formulation meeting stability standards. Phase 1 showed the lotion was well tolerated with no adverse reactions, positive sensorial perception, and a promising once-a-day pharmacokinetic profile. Patent US11833141 granted.

IN PROGRESS

Phase 2a/2b Bridge

Evaluating safety and efficacy in children with moderate-to-severe atopic dermatitis, with several regional CRO partners collaborating. Target study start Q4 2026 and completion Q2 2027. Strategic collaborators welcome.

NEXT

Phase 3 & Product Release

Planning for parallel studies, including FDA engagement, following Phase 2 success. Evaluating OTC and prescription versions based on target-market needs. Target: 2028.

Invest or Partner With Us

We are seeking strategic investors and clinical partners who share our vision of bringing innovative, accessible dermatology treatments to patients worldwide. We also welcome enquiries about participation in our clinical development programme.